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Efficient isolation of tubulin mutants in Chlamydomonas
Mar. 2023 *Kudos (a Research showcase)
Exploring Cellular Functions Using Micro Green Algae
Jul. 4, 2019 ChuoOnline (by The Yomiuri Shimbun Advertising Bureau)
Cell movements are produced and regulated by cytoskeletons, motor proteins, and their regulatory proteins. These proteins are precisely controlled in expression and localization within the cell. Flagella/cilia consist of more than 500 regularly arranged proteins. Defects in flagella/cilia cause serious genetic diseases such as situs inversus and sterility. Our laboratory is studying the molecular mechanisms of ciliogenesis, cilia/flagella motility and cytoskeletal dynamics in general, using
Chlamydomonas (a model organism for cilia/flagella studies) and cultured epithelial cells. Our laboratory employs a variety of cell biological and biochemical techniques, as well as phylogenetic analysis.
Chlamydomonas reinhardtii and other volvocalean species.
Xenopus laevis kidney-derived cells (A6 cells) grow primary cilia.